DNA-encoded chemical library (DEL) has emerged as a powerful technology for ligand discovery in biomedical research. Recently, we have developed a DNA-encoded dynamic library (DEDL) approach by incorporating the concept of dynamic combinatorial library (DCL) with DELs.
DEDL has shown excellent potential in ligand discovery towards a variety of protein targets. However, the requirement of having a pair of unnatural p-stilbazoles as the interstrand DNA crosslinker has limited the chemical diversity of DEDLs. Here, we replaced p-stilbazole with psoralen (PS) and tested the feasibility of psoralen as the crosslinker in DEDL selection.
Since psoralen is commercially available and does not require any special crosslinking partner, existing DELs may be directly used to create high-diversity DEDLs. This study is expected to greatly facilitate the development of DEDLs as a versatile tool in drug discovery.
KT 5823 |
|
B6673-.05 |
ApexBio |
50 µg |
EUR 76 |
|
|
|
Description: MAPK Signaling|Protein Kinase G |
KT 5823 |
|
B6673-.1 |
ApexBio |
100 µg |
EUR 120 |
|
|
|
Description: MAPK Signaling|Protein Kinase G |
KT 5823 |
|
B6673-.25 |
ApexBio |
250 µg |
EUR 249 |
|
|
|
Description: protein kinase G inhibitor |
KT 5823 |
|
B6673-.5 |
ApexBio |
500ug |
EUR 468 |
|
Description: MAPK Signaling|Protein Kinase G |
KT 5720 |
|
B9002-.05 |
ApexBio |
50 µg |
EUR 101.6 |
|
|
|
Description: MAPK Signaling|PKA |
KT 5720 |
|
B9002-.1 |
ApexBio |
100 µg |
EUR 193.6 |
|
|
|
Description: MAPK Signaling|PKA |
KT 5720 |
|
B9002-.25 |
ApexBio |
250 µg |
EUR 459.2 |
|
|
|
Description: MAPK Signaling|PKA |
KT 5720 |
|
B9002-.5 |
ApexBio |
500 µg |
EUR 815.2 |
|
|
|
Description: MAPK Signaling|PKA |
KT-5720 |
|
abx076628-250l |
Abbexa |
250 µl |
EUR 212.5 |
KT-5720 |
|
abx076628-500l |
Abbexa |
500 µl |
EUR 487.5 |
KT 5823 |
|
20-abx076629 |
Abbexa |
-
Ask for price
-
Ask for price
|
|
|
|
KT-5823 |
|
abx076629-250l |
Abbexa |
250 µl |
EUR 168.75 |
KT-5823 |
|
abx076629-500l |
Abbexa |
500 µl |
EUR 462.5 |
KT-531 |
|
HY-128436 |
MedChemExpress |
5mg |
EUR 498.93 |
|
Description: KT-531 is a potent and selective inhibitor of HDAC6 with an IC50 of 8.5 nM. KT-531 exhibits strong inhibition against SUP-T11 cells with an IC50 of 0.42 μM. KT-531 can be used in study hematological cancers[1]. |
KT-474 |
|
HY-145483 |
MedChemExpress |
1 mg |
EUR 9415.73 |
|
Description: KT-474 (KYM-001) is an orally active PROTAC IRAK4 degrader with antitumor activities[1]. KT-474 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. |
KT-362 fumarate |
|
MBS5777458-5mg |
MyBiosource |
5(mg |
EUR 915 |
KT-362 fumarate |
|
MBS5777458-5x5mg |
MyBiosource |
5x5(mg |
EUR 3970 |
KT-362 fumarate |
|
T27753-10mg |
TargetMol Chemicals |
10mg |
Ask for price |
|
|
|
Description: KT-362 fumarate |
KT-362 fumarate |
|
T27753-50mg |
TargetMol Chemicals |
50mg |
Ask for price |
|
|
|
Description: KT-362 fumarate |
Forchlorfenuron (KT-30, CPPU) |
|
C7187-1000 |
ApexBio |
1g |
EUR 68 |
|
|
|
Description: Others |
Forchlorfenuron (KT-30, CPPU) |
|
C7187-500 |
ApexBio |
500mg |
EUR 40 |
|
|
|
Description: Others |
Forchlorfenuron (KT-30 CPPU) |
|
MBS3610270-100mg |
MyBiosource |
100mg |
EUR 215 |
Forchlorfenuron (KT-30 CPPU) |
|
MBS3610270-500mg |
MyBiosource |
500mg |
EUR 240 |
Forchlorfenuron (KT-30 CPPU) |
|
MBS3610270-50mg |
MyBiosource |
50mg |
EUR 200 |
Forchlorfenuron (KT-30 CPPU) |
|
MBS3610270-5x500mg |
MyBiosource |
5x500mg |
EUR 750 |
Forchlorfenuron (KT-30, CPPU) |
|
MBS5751941-500mg |
MyBiosource |
500mg |
EUR 145 |
Forchlorfenuron (KT-30, CPPU) |
|
MBS5751941-5x500mg |
MyBiosource |
5x500mg |
EUR 500 |
Plasminogen Receptor (KT) (PLGRKT) Antibody |
|
abx318476-100l |
Abbexa |
100 µl |
EUR 250 |
Plasminogen Receptor (KT) (PLGRKT) Antibody |
|
20-abx318476 |
Abbexa |
-
Ask for price
-
Ask for price
-
Ask for price
-
Ask for price
-
Ask for price
|
- 20 ug
- 50 ug
- 100 ug
- 200 ug
- 1 mg
|
|
|
Plasminogen Receptor (KT) (PLGRKT) Antibody |
|
abx318476-50l |
Abbexa |
50 µl |
EUR 162.5 |
Recombinant Rat Plasminogen receptor (KT) |
|
MBS1142402-INQUIRE |
MyBiosource |
INQUIRE |
Ask for price |
11-KT(11-ketoTestosterone)ELISAKit |
|
ELK8908-48T |
ELK Biotech |
48T |
EUR 160 |
|
|
|
Description: Competitive Inhibition |
11-KT(11-ketoTestosterone)ELISAKit |
|
ELK8908-96T |
ELK Biotech |
96T |
EUR 229 |
|
|
|
Description: Competitive Inhibition |
Recombinant Rat Plasminogen receptor (KT) |
|
MBS7039515-002mg |
MyBiosource |
0.02mg |
EUR 1420 |
Recombinant Rat Plasminogen receptor (KT) |
|
MBS7039515-01mg |
MyBiosource |
0.1mg |
EUR 2385 |
Recombinant Rat Plasminogen receptor (KT) |
|
MBS7039515-5x01mg |
MyBiosource |
5x0.1mg |
EUR 10690 |
Recombinant Mouse Plasminogen receptor (KT) |
|
MBS7038675-002mg |
MyBiosource |
0.02mg |
EUR 1420 |
Recombinant Mouse Plasminogen receptor (KT) |
|
MBS7038675-01mg |
MyBiosource |
0.1mg |
EUR 2385 |
Recombinant Mouse Plasminogen receptor (KT) |
|
MBS7038675-5x01mg |
MyBiosource |
5x0.1mg |
EUR 10690 |
6-KT Storage Solution (Sterile) |
|
K8331 |
Solarbio Life Science |
-
Ask for price
-
Ask for price
-
Ask for price
-
Ask for price
|
- 5 mL
- 10 mL
- 5x 1 mL
- 100 mL
|
Recombinant Rat Plasminogen receptor (KT), partial |
|
MBS7069426-INQUIRE |
MyBiosource |
INQUIRE |
Ask for price |
Recombinant Human Plasminogen receptor (KT) (C9orf46) |
|
MBS7010620-002mg |
MyBiosource |
0.02mg |
EUR 1420 |
Recombinant Human Plasminogen receptor (KT) (C9orf46) |
|
MBS7010620-01mg |
MyBiosource |
0.1mg |
EUR 2385 |
Recombinant Human Plasminogen receptor (KT) (C9orf46) |
|
MBS7010620-5x01mg |
MyBiosource |
5x0.1mg |
EUR 10690 |
Recombinant Mouse Plasminogen receptor (KT), partial |
|
MBS7099101-INQUIRE |
MyBiosource |
INQUIRE |
Ask for price |
B30C-4000-483OR-KT AF Systems Consumables |
|
139928 |
BRADY NV |
Box of 1 Roll |
EUR 563.88 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
B30C-2250-483OR-KT AF Systems Consumables |
|
139929 |
BRADY NV |
Box of 1 Roll |
EUR 415.4 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
B30C-1125-483OR-KT AF Systems Consumables |
|
139930 |
BRADY NV |
Box of 1 Roll |
EUR 274.35 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
B30C-4000-483BK-KT AF Systems Consumables |
|
139931 |
BRADY NV |
Box of 1 Roll |
EUR 563.88 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
B30C-2250-483BK-KT AF Systems Consumables |
|
139932 |
BRADY NV |
Box of 1 Roll |
EUR 415.4 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
B30C-1125-483BK-KT AF Systems Consumables |
|
139933 |
BRADY NV |
Box of 1 Roll |
EUR 274.35 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
B30C-4000-483GN-KT AF Systems Consumables |
|
139934 |
BRADY NV |
Box of 1 Roll |
EUR 563.88 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
B30C-2250-483GN-KT AF Systems Consumables |
|
139935 |
BRADY NV |
Box of 1 Roll |
EUR 415.4 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
B30C-1125-483GN-KT AF Systems Consumables |
|
139936 |
BRADY NV |
Box of 1 Roll |
EUR 274.35 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
B30C-4000-483BL-KT AF Systems Consumables |
|
139937 |
BRADY NV |
Box of 1 Roll |
EUR 563.88 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
B30C-2250-483BL-KT AF Systems Consumables |
|
139938 |
BRADY NV |
Box of 1 Roll |
EUR 415.4 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
B30C-1125-483BL-KT AF Systems Consumables |
|
139939 |
BRADY NV |
Box of 1 Roll |
EUR 274.35 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
B30C-4000-483RD-KT AF Systems Consumables |
|
139940 |
BRADY NV |
Box of 1 Roll |
EUR 563.88 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
B30C-2250-483RD-KT AF Systems Consumables |
|
139941 |
BRADY NV |
Box of 1 Roll |
EUR 415.4 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
B30C-1125-483RD-KT AF Systems Consumables |
|
139942 |
BRADY NV |
Box of 1 Roll |
EUR 274.35 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
B30C-4000-483YL-KT AF Systems Consumables |
|
139943 |
BRADY NV |
Box of 1 Roll |
EUR 563.88 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
B30C-3000-483YL-KT AF Systems Consumables |
|
139944 |
BRADY NV |
Box of 1 Roll |
EUR 473.22 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
B30C-2250-483YL-KT AF Systems Consumables |
|
139945 |
BRADY NV |
Box of 1 Roll |
EUR 415.4 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
B30C-1125-483YL-KT AF Systems Consumables |
|
139946 |
BRADY NV |
Box of 1 Roll |
EUR 274.35 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
B30C-4000-483WT-KT AF Systems Consumables |
|
139947 |
BRADY NV |
Box of 1 Roll |
EUR 563.88 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
B30C-3000-483WT-KT AF Systems Consumables |
|
139948 |
BRADY NV |
Box of 1 Roll |
EUR 473.22 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
B30C-2250-483WT-KT AF Systems Consumables |
|
139949 |
BRADY NV |
Box of 1 Roll |
EUR 415.4 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
B30C-1125-483WT-KT AF Systems Consumables |
|
139950 |
BRADY NV |
Box of 1 Roll |
EUR 274.35 |
|
Description: Description Dutch: ToughStripe-vloertape voor BBP35/BBP37/S3xxx/i3300-printers; Description French: Ruban de marquage au sol ToughStripe pour imprimantes BBP35/BBP37/S3xxx/i3300 |
Human Plasminogen Receptor (KT) (PLGRKT) ELISA Kit |
|
abx539314-96tests |
Abbexa |
96 tests |
EUR 687.5 |
Mouse Plasminogen Receptor (KT) (PLGRKT) ELISA Kit |
|
abx539315-96tests |
Abbexa |
96 tests |
EUR 687.5 |
Rat Plasminogen Receptor (KT) (PLGRKT) ELISA Kit |
|
abx539316-96tests |
Abbexa |
96 tests |
EUR 687.5 |
Fish 11-keto Testosterone (KT) ELISA Kit |
|
AE58425FI-48T |
Abebio |
48T |
EUR 290 |
|
|
|
Description: Fish |
Fish 11-keto Testosterone (KT) ELISA Kit |
|
AE58425FI-48Tests |
Abebio |
48 Tests |
EUR 290 |
|
|
|
Description: Fish |
Fish 11-keto Testosterone (KT) ELISA Kit |
|
AE58425FI-96T |
Abebio |
96T |
EUR 540 |
|
|
|
Description: Fish |
Fish 11-keto Testosterone (KT) ELISA Kit |
|
AE58425FI-96Tests |
Abebio |
96 Tests |
EUR 540 |
|
|
|
Description: Fish |
Fish 11-Ketotestosterone,11-KT ELISA KIT |
|
JOT-EKA0041FI |
Jotbody |
96 wells |
EUR 398.4 |
|
Description: Fish |
Human 11-Ketotestosterone,11-KT ELISA KIT |
|
JOT-EKA3107Hu |
Jotbody |
96 wells |
EUR 366.4 |
|
Description: Human |
Human 11-Ketotestosterone,11-KT ELISA KIT |
|
JOT-EK5106Hu |
Jotbody |
96 wells |
Ask for price |
|
Description: Human |
Human 11-Ketotestosterone, 11-KT GENLISA ELISA |
|
KBH5106 |
Krishgen |
1 x 96 wells |
EUR 286 |
Fish 11-keto Testosterone (KT) ELISA Kit |
|
EK11227 |
SAB |
96Т |
EUR 799 |
|
|