Signal Amplification Methods

Summary Signal amplification methods were initially designed as an alternative to target amplification technologies, such as polymerase chain reaction (PCR), to minimize the possibility of contamination by target amplification products. Unlike target amplification, signal amplification methods (as defined herein) do not rely on enzymes for amplification. Probe-based amplification techniques, such as cleavage-based amplification and rolling … Read more

Second Messenger System

Second messenger, a molecule within cells that acts to transmit signals from a receptor to a target. The term second messenger was coined with the discovery of these substances to distinguish them from hormones and other molecules that function outside the cell as “first messengers” in the transmission of biological information. Many second messenger molecules … Read more

Proton Pump Inhibitors

Proton-pump inhibitor Proton pump inhibitors (PPIs) are medications that work by reducing the amount of stomach acid produced by glands in the lining of the stomach. How PPIs Help You Proton pump inhibitors are used to: Relieves symptoms of acid reflux or gastroesophageal reflux disease (GERD). This is a condition in which food or liquid … Read more