Evidence of protein binding by a nucleopeptide based on a thymine-decorated L-diaminopropanoic acid through CD and in silico studies

Evidence of protein binding by a nucleopeptide based on a thymine-decorated L-diaminopropanoic acid through CD and in silico studies

Nucleopeptides are chimeric compounds of biomedical significance carrying DNA nucleobases anchored to peptide backbones with ascertained capability to bind nucleic acids. However, their capability to work together with proteins concerned in pathologies of social relevance is a function that also requires investigation. The worrying scenario at present noticed worldwide for the COVID-19 pandemic urgently requires the analysis … Read more

Current trends in flow cytometry automated data analysis software

Current trends in flow cytometry automated data analysis software

Automated flow cytometry (FC) data analysis instruments for cell inhabitants identification and characterization are more and more getting used in educational, biotechnology, pharmaceutical, and scientific laboratories. The improvement of those computational strategies is designed to beat reproducibility and course of bottleneck points in guide gating, nevertheless, the take-up of those instruments stays (anecdotally) low. Here, … Read more

Towards medical knowmetrics: representing and computing medical knowledge using semantic predications as the knowledge unit and the uncertainty as the knowledge context

Towards medical knowmetrics: representing and computing medical knowledge using semantic predications as the knowledge unit and the uncertainty as the knowledge context

In China, Prof. Hongzhou Zhao and Zeyuan Liu are the pioneers of the idea “knowledge unit” and “knowmetrics” for measuring knowledge. However, the definition on “computable knowledge object” stays controversial up to now in several fields. For instance, it’s outlined as (1) quantitative scientific idea in pure science and engineering, (2) knowledge level in the … Read more

Novel nanomaterial-organism hybrids with biomedical potential

Novel nanomaterial-organism hybrids with biomedical potential

Instinctive hierarchically biomineralized constructions of assorted organisms, reminiscent of eggs, algae, and magnetotactic micro organism, afford further safety and distinct efficiency, which endow fragile organisms with a tenacious means to adapt and survive. However, spontaneous formation of hybrid supplies is troublesome for many organisms in nature. Rapid improvement of chemistry and supplies science efficiently obtained … Read more

Cytotoxicity and Toxicological Studies of Artocarpus altilis Extracts, Inducing Apoptosis and Cell Cycle Arrest via CASPASE-3 and CASPASE-8 Pathways Against Human Breast MCF-7 Cells

Cytotoxicity and Toxicological Studies of Artocarpus altilis Extracts, Inducing Apoptosis and Cell Cycle Arrest via CASPASE-3 and CASPASE-8 Pathways Against Human Breast MCF-7 Cells

In current biomedical analysis, the world of most cancers and infectious illnesses has a number one place within the utilization of medicinal crops as a supply of drug discovery. Malaysia has a variety and a big quantity of underutilized fruits which are wealthy in phenolic compounds. Artoarpus altilis think about an underutilized fruit that’s wealthy in phenolic compounds. … Read more